Перегляд за автором "Alexeeva, I.V."

Результати 1-3 з 3

Inhibition of in vitro transcription by 2-arylidene derivatives of thiazolo[3,2-α]benzimidazol-3(2H)-one

Palchykovska, L.G.; Alexeeva, I.V.; Negrutska, V.V.; Kostyuk, Yu.K.; Indychenko, T.M.; Kostenko, O.M.; Kryvorotenko, D.V.; Shved, A.D.; Dubey, I.Ya. (Вiopolymers and Cell, 2010)

Aim. To evaluate a series of 2-substituted thiazolo[3,2-α]benzimidazolones as potential transcription inhibitors. Methods. Compounds were tested in a model transcription system based on T7 RNA polymerase. Results. The ...
Synthesis and study on biological activity of nitrogen-containing heterocyclic compounds – regulators of enzymes of nucleic acid biosynthesis

Alexeeva, I.V.; Shved, A.D. (Вiopolymers and Cell, 2013)

Results of investigations on the development of new regulators of functional activity of nucleic acid biosynthesis enzymes based on polycyclic nitrogen-containing heterosystems are summarized. Computer design and molecular ...
Telomerase inhibition by new di- and trisubstituted acridine derivatives

Negrutska, V.V.; Saraieva, I.V.; Kostina, V.G.; Alexeeva, I.V.; Lysenko, N.A.; Dubey, I.Ya. (Вiopolymers and Cell, 2016)

Aim. To study a series of new acridine derivatives containing two basic fragments able to bind to quadruplex DNA at C-4 and C-9 positions as potential telomerase inhibitors. Methods. TRAP assay was used to determine the ...

Результати 1-3 з 3

Пошук